Stereospecific synthesis of (±)-sesbanine and its C-10 epimer

✍ Scribed by Andrew S. Kende; Thomas P. Demuth

• Publisher: Elsevier Science
• Year: 1980
• Tongue: French
• Weight: 221 KB
• Volume: 21
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)71454-7

✦ Synopsis

A short, stereospecific total synthesis of (+)-sesbanine and its C-10 epimer from 4-methylnicotinonitrile is described.

Ethanolic seed extracts from Sesbania drunnaondii (Leguminosae) are known to possess antileukemic activity.' Powell, Clardy and their collaborators