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Stereospecific synthesis of new steroidal isoxazoles in dry media

✍ Scribed by María Guadalupe Hernández-Linares; Jesús Sandoval-Ramírez; Socorro Meza-Reyes; Sara Montiel-Smith; Gabriel Guerrero-Luna


Book ID
116892681
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
515 KB
Volume
76
Category
Article
ISSN
0039-128X

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Trimolecular condensation of N-(3-methyl-5-styryl-isoxazol-4-yl)-N'-aryl thioureas (2), paraformaldehyde and primary amines using montmorillonite K-10 in dry media under microwave irradiation leads to isoxazolyl triazinethiones (3) in high yield. Condensation of 2 with paraformaldehyde alone under s