Stereospecific synthesis of new 2,3,4,5-piperidinetetracarboxylic acids and 2,3,5-piperidinetricarboxylic acids

✍ Scribed by Yasushi Arakawa; Tomoaki Murakami; Fumiko Ozawa; Yukimi Arakawa; Shigeyuki Yoshifuji

• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 218 KB
• Volume: 59
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(03)01200-6

✦ Synopsis

Diels-Alder adducts of 1,2-dihydropyridine with maleic and acrylic acid derivatives were stereospecifically converted by way of RuO 4 oxidation into new r-2,c-3,c-4,c-5-piperidinetetracarboxylic acid, r-2,t-3,t-4,c-5-piperidinetetracarboxylic acid, r-2,c-3,c-5piperidinetricarboxylic acid, and r-2,t-3,c-5-piperidinetricarboxylic acid.