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Stereospecific Synthesis of 2,2,3-Trisubstituted Tetrahydroquinolines: Application to the Total Syntheses of Benzastatin E and Natural Virantmycin.

โœ Scribed by Mayuko Ori; Narihiro Toda; Kazuko Takami; Keiko Tago; Hiroshi Kogen


Publisher
John Wiley and Sons
Year
2005
Weight
28 KB
Volume
36
Category
Article
ISSN
0931-7597

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Stereospecific Construction of Contiguou
โœ Mayuko Ori; Narihiro Toda; Kazuko Takami; Keiko Tago; Hiroshi Kogen ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 124 KB

The stereoselective construction of chiral quaternary stereocenters is one of the most challenging problems in synthetic organic chemistry. [1] Substituted tetrahydroquinolines and tetrahydroisoquinolines have attracted considerable attention from organic and medicinal chemists, primarily because th