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Stereospecific reduction of diastereomerically pure menthyl phosphinates: a new route to optically active phosphine oxides

✍ Scribed by Yasuhiro Koide; Atsushi Sakamoto; Tsuneo Imamoto


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
140 KB
Volume
32
Category
Article
ISSN
0040-4039

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✦ Synopsis


Diastereomerically pure menthyl phosphinates are stereospecifically reduced by lithium 4,4'-di-fertbutylbiphenylide.

Subsequent treatment with alkyl halides affords phosphine oxides with high optical purity.