The titled amino alcohols are obtained by treatment of chiral amino acids with triallylborane. Electrophylic iodocyclization of the alcohols leads to pyrrolidine derivatives. @ 1997 Elsevier Science Ltd. Optically active 2-amino alcohols are widely used in organic synthesis as chiral inductors,l-3
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Stereospecific Rearrangements During the Synthesis of Pyrrolidines and Related Heterocycles from Cyclizations of Amino Alcohols with Vinyl Sulfones.
โ Scribed by Thomas G. Back; Masood Parvez; Huimin Zhai
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 233 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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