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Stereospecific protein kinase C activation by photolabile diglycerides

✍ Scribed by R. Sreekumar; Y.Q. Pi; X.P. Huang; J.W. Walker

Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
324 KB
Volume
7
Category
Article
ISSN
0960-894X

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✦ Synopsis

The synthesis and photochemistry of diglycefides designed to photolyze to bioactive diacylglycerols and optimized for facile incorporation into biological membranes is described. Stereospecific activation of protein kinase C in vitro and in living cells is demonstrated.

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