Stereospecific pharmacodynamics and chiral inversion of NG-nitro-arginine in the beagle dogs
β Scribed by Yan-Fei Xin; Li-Qiang Gu; Sheng Zhang; Yun-Sheng Bai; Guo-Liang Zhou; Zhen-Qiang You; Yao-Xian Xuan
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 284 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0899-0042
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## Abstract **BACKGROUND:** To test whether the differentiating embryo is susceptible to the teratogenic effects of the nitric oxide (NO) synthesis inhibitor N^G^βnitroβLβarginine methyl ester (LβNAME). **METHODS:** ICRβ(CDβ1) mice received a single intraperitoneal injection of LβNAME at 90, 150, o