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Stereospecific functionalization of (R)-(−)-1,1′-bi-2-naphthol triflate

✍ Scribed by Lilia Kurz; Gary Lee; David Morgans Jr.; Michael Joe Waldyke; Timothy Ward


Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
270 KB
Volume
31
Category
Article
ISSN
0040-4039

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Efficient synthesis of 6-mono-bromo-1,1′
✍ Dongwei Cai; Robert D Larsen; Paul J Reider 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 73 KB

Through mono-ester formation of 1,1%-bi-2-naphthol (BINOL) with pivaloyl chloride the selective mono-bromination was achieved cleanly on the other ring to afford 6-mono-bromo-1,1%-bi-2-naphthol in an efficient 86% yield.