From Central to Axial to Central Chirali
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Georgi Stavrakov; Manfred Keller; Bernhard Breit
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Article
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2007
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John Wiley and Sons
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English
β 278 KB
π 2 views
## Abstract Enantioselective synthesis of the core __trans__β4,5,9,10βtetrahydroxyβ9,10βdihydrophenanthrene parent system of the antibiotics benanimicin, pradimicin and FD 594 has been accomplished. The synthesis employs a chiral tether approach and makes use of efficient central to axial to centra