Stereoselectivity of Superacid-Catalyzed Pictet−Spengler Cyclization Reactions
✍ Scribed by Nakamura, Satoshi; Tanaka, Masaru; Taniguchi, Tooru; Uchiyama, Masanobu; Ohwada, Tomohiko
- Book ID
- 120834635
- Publisher
- American Chemical Society
- Year
- 2003
- Tongue
- English
- Weight
- 118 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1523-7060
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## Abstract Under catalysis of diphenylphosphate, tryptamine undergoes a two‐step one‐pot reaction with 1,3‐dicarbonyl compounds and α,β‐unsaturated aldehydes to give the title compounds bearing two chiral centers as almost single diastereomers (< 95% d.e.).
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