✦ LIBER ✦
Stereoselectivity of horse liver alcohol dehydrogenase catalyzed oxidoreduction of an organometallic meso diol and the corresponding dialdehyde
✍ Scribed by Yoshimitsu Yamazaki; Kuniaki Hosono
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 141 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
1,2_Bis(hydroxymethyl)ferrocene was oxidized by horse liver alcohol dehydrogenase preferentially to (lR, 2S)-(hydroxymethyl)aldehyd, while 1,2_diformylferrocene was reduced to the (12, 2!)-antipode, The usefulness of enzymes as catalysts for asymmetric synthesis has been widely recognized.
1 However, most of the substrates so far treated are conventional compounds made