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Stereoselectivity in central analgesic action of tocainide and its analogs

✍ Scribed by Dr. Carlo Franchini; Francesca Chiaia Noja; Filomena Corbo; Giovanni Lentini; Vincenzo Tortorella; Alessandro Bartolini; Carla Ghelardini; Rosanna Matucci; Alberto Giotti

Book ID
102799028
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
626 KB
Volume
5
Category
Article
ISSN
0899-0042

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πŸ“œ SIMILAR VOLUMES

Stereoselective interaction of tocainide
Stereoselective interaction of tocainide and its chiral analogs with the sodium channels in human myoballs
✍ D. Tricarico; B. Fakler; W. Spittelmeister; J. P. Ruppersberg; R. StΓΌtzel; C. Fr πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 868 KB

The effects of both enantiomers of tocainide and of some of its chiral analogs on the inactivation of the sodium current in human myoballs were investigated with the whole-cell recording technique. Structure and electron densities of the applied compounds were calculated and compared to the results.