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Stereoselective uptake of the GABA-transaminase inhibitors gamma-vinyl gaba and gamma-acetylenic GABA into neurons and astrocytes

โœ Scribed by Arne Schousboe; Orla M. Larsson; Nikolaus Seiler

Publisher
Springer
Year
1986
Tongue
English
Weight
485 KB
Volume
11
Category
Article
ISSN
0364-3190

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Uptake of GABA and nipecotic acid in ast
Uptake of GABA and nipecotic acid in astrocytes and neurons in primary cultures: Changes in the sodium coupling ratio during differentiation
โœ O.M. Larsson; L. Hertz; Dr. A. Schousboe ๐Ÿ“‚ Article ๐Ÿ“… 1986 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 695 KB

The coupling ratio between sodium and GABA or the GABA analog, (RS)- nipecotic acid, in neuronal and glial uptake of GABA or nipecotic acid was investigated as a function of the morphological differentiation of these cell types in primary cultures. Both in neurons and astrocytes a high-affinity upta