Stereoselective Transformation of 2H-1,4-Oxazin-2-ones into 2,(2),5,5-Tri- and Tetrasubstituted Analogues of cis-5-Hydroxy-2-piperidinemethanol and cis-5-Hydroxy-6-oxo-2-piperidinecarboxylic Acid
✍ Scribed by Xiujuan Wu; Kristof Dubois; Joeri Rogiers; Suzanne Toppet; Frans Compernolle; Georges J Hoornaert
- Book ID
- 108370796
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 240 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
Various analogues of cis-5-amino-6-oxo-2-piperidinemethanol and cis-5-amino-2-piperidinemethanol have been prepared via Diels -Alder reaction of substituted pyrazinones with ethene followed by acid methanolysis of the bridged lactam adducts. Further reduction of the resulting methyl 2-piperidinecarb
## Abstract Dehydrochlorination of chlorinated 5‐hydroxy‐2‐oxabicyclo[3.2.0]heptan‐4‐ones, 3a‐c, which were obtained from the photo[2+2]cycloadditions between 4‐hydroxy‐3(2__H__)‐furanone 1 and chloroethylenes, with triethylamine gave 2‐ethenyl‐3(2__H__)‐furanones 4a,b or 2‐(2‐cyanoethyl)‐3(2__H__)