Stereoselective total synthesis of racemic β-eudesmol
✍ Scribed by James A. Marshall; Myron T. Pike
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- French
- Weight
- 304 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
B-Eudesmol (l3) occupies a central position In the eudesmane group of sesquiterpenes because of Its extensive use in structural and stereochemical correlations.' For example, it is this substance which provides the conf'igurational link between terpenes and steroids.2 We delineate in this communication a stereoselective total synthesis ofthe racemic form of B-eudesmol by a route which, through modification at the terminal stages, could be applied to other members of the eudesmane group.
📜 SIMILAR VOLUMES
Eudeemol has long been recognised as being a mixture of two isomers, a-and B\_, formulated on degradative evidence as ( 1) and (2) respectively.' A third isomer, Y-eudesmol (3). is also present in some samples of commercial eudesmol.
The sesquiterpene nootkatone (3, a citrus constituent whose characteristic flavor and odor properties hold some commercial interest, has been the subject of recent synthetic investigations in several laboratories.