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Stereoselective synthesis of α-l-bicarbocyclic nucleosides as potential antiviral drugs

✍ Scribed by Christine Demaison; Christophe Hourioux; Philippe Roingeard; Luigi A. Agrofoglio

Book ID
108387204
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
220 KB
Volume
39
Category
Article
ISSN
0040-4039

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Synthesis of bicarbocyclic dideoxynucleo
Synthesis of bicarbocyclic dideoxynucleosides as potential antiviral agents
✍ Qi Chao; Vasu Nair 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 707 KB

Two novel classes of bicarbocyclic dideoxynucleosides have been synthesized for antiviral studies. The key intermediates, 9 and 23, synthesized in multiple steps from readily available monocyclic or bicyclic precursors, were coupled with the desired heterocyclic bases to afford, after further elabor