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Stereoselective Synthesis of ( Z )- and ( E )-Allylic Silanes by Copper-Mediated Substitution Reactions of Allylic Carbamates with Grignard Reagents

โœ Scribed by Smitrovich, Jacqueline H.; Woerpel, K. A.


Book ID
121749505
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
421 KB
Volume
65
Category
Article
ISSN
0022-3263

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The first copper-catalyzed allylic substitution reactions of allylic acetates and carbamates employing a bis(triorganosilyl)zinc reagent are reported. This novel procedure avoids the use of stoichiometric amounts of copper salts which are usually mandatory with this chemistry. Application of this me