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Stereoselective synthesis of Z-alkenes from α-methylcrotylstannanes and aldehydes

✍ Scribed by Caroline Hull; Simon V. Mortlock; Eric J. Thomas


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
240 KB
Volume
28
Category
Article
ISSN
0040-4039

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Stereoselective synthesis of methyl (Z)-
✍ Rachid Baati; Charles Mioskowski; Dhurke Kashinath; Sanjeevarao Kodepelly; Biao 📂 Article 📅 2009 🏛 Elsevier Science 🌐 French ⚖ 217 KB

Methyl (Z)-a-methoxyacrylates are generated in good yields by a mild, stereospecific two-carbon homologation of a wide variety of aldehydes utilizing commercial methyl 2,2-dichloro-2-methoxyacetate and CrCl 2 under Barbier conditions at room temperature. A rational mechanism based upon a Reformatsky