✦ LIBER ✦
Stereoselective synthesis of threo-3-hydroxycarboxylic acids. Stereocheminstry of an aldoltype addition under kinetic and thermodynamic control.
✍ Scribed by Johann Mulzer; Johann Segner; Gisela Brüntrup
- Book ID
- 104235889
- Publisher
- Elsevier Science
- Year
- 1977
- Tongue
- French
- Weight
- 246 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The addition of preformed enolates 1 to carbonyl compounds 2 results in the formation of metal chelates, which, having stereocenters at C-2 and C-5, are generally formed as mixtures of the threoand erythro-isomers 2 and 4'.