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Stereoselective Synthesis of the β-Anomer of 4‘-Thionucleosides Based on Electrophilic Glycosidation to 4-Thiofuranoid Glycals

✍ Scribed by Haraguchi, Kazuhiro; Takahashi, Haruhiko; Shiina, Noriaki; Horii, Chikafumi; Yoshimura, Yuichi; Nishikawa, Ayako; Sasakura, Eiko; Nakamura, Kazuo T.; Tanaka, Hiromichi


Book ID
111898055
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
292 KB
Volume
67
Category
Article
ISSN
0022-3263

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Synthesis of 4-thiofuranoid 1,2-glycals
✍ J.Allen Miller; Ashley W Pugh; G.Mustafa Ullah 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 97 KB

Convenient one-pot procedures using iodine monochloride have been developed for the preparation of two 4thio-1,2-glycals from readily available starting materials and for their β-anomer selective conversion into 2 -iodo-4 -thionucleosides. Conditions for the reductive de-iodination of these iodonucl