๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Stereoselective synthesis of the (R)- and (S)-1-(2-amino-3-nitrophenoxy)-3-(tert-butylamino)-2-propanol from the enantiomeric glycidyl tosylates

โœ Scribed by Akli Hammadi; Christian Crouzel


Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
181 KB
Volume
1
Category
Article
ISSN
0957-4166

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


A Practical Synthesis of the Dihydroxyet
โœ William R. Baker; Stephen L. Condon ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 249 KB

The N-Boc dihydroxyethylene dipeptide isostere 7 and its N-Boc 3-(thiazol-4-ylJalany1 derivative 8 were synthesized, without purification of intermediates, from (4S~R)-22-dimethyl-4-(2-methy~propylJ-5-hydro~~thyl-l.3-dioxolane (361, in 24 and 32% overall yield, respectively, Alcohol 38 was readily p

A facile stereospecific synthesis of the
โœ Satya S. Murthy; Wendel L. Nelson ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 263 KB

## Abstract Enantiomers of metoprolol containing six deuterium atoms in the isopropyl methyl groups were prepared in two steps from the sodium salt of 4โ€(2โ€methoxyethyl)phenol (3) and the commercially available (2__R__)โ€ and (2__S__)โ€glycidyl 3โ€nitrobenzenesulfonates [(2__R__)โ€2 and (2__S__)โ€2]. Th

A novel synthesis of the (2R,3S)- and (2
โœ Yuko Kobayashi; Yoshiji Takemoto; Yoshio Ito; Shiro Terashima ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 317 KB

The title synthesis could be accomplished by featuring the [2+21-cycloaddition reaction of a chiral imine with benzyloxyketene, alcoholysis of the formed 2-azetidinone derivative, and reductive removal of the mandelate-derived benzylic oxygen by way of a 2-oxazolidone derivative. Optically active 3