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Stereoselective Synthesis of the Fully Functionalized Core Fragment (I) of Terpentecin (II).

โœ Scribed by Taotao Ling; Fatima Rivas; Emmanuel A. Theodorakis


Publisher
John Wiley and Sons
Year
2003
Weight
70 KB
Volume
34
Category
Article
ISSN
0931-7597

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โœ Zuozhong ZHOU; Dong SUO; Zhenyu YANG; Lin CHEN; Taishan HU; Zhujun YAO ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 110 KB

A stereoselective synthesis of all functionalized C2-C10 fragment 13 of the antitumor marine natural product clavulactone was accomplished, starting from the commercially available 3-methylglutaric acid anhydride. Desymmetrization of 3-methylglutaric acid anhydride with (S)-ฮฑ-phenylethanamine was su