Stereoselective synthesis of the dihydroxyisoleucine constituent of the amanita mushroom toxins

✍ Scribed by Paul A. Bartlett; Donna J. Tanzella; James F. Barstow

• Book ID: 104220405
• Publisher: Elsevier Science
• Year: 1982
• Tongue: French
• Weight: 212 KB
• Volume: 23
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)86905-1

✦ Synopsis

Ester-enolate

Claisen rearrangement of cis-crotyl N-_t-Boc-glycinate and iodOlaCtOnization of the N-phthaloyl derivative of theresulting unsaturated acid are used as the stereocontrolling steps in a synthesis of the title compound.