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Stereoselective Synthesis of the Cyclic Ether Core of (+)-Laurenyne.

โœ Scribed by J. Stephen Clark; Rebecca P. Freeman; Monica Cacho; Andrew W. Thomas; Steven Swallow; Claire Wilson


Publisher
John Wiley and Sons
Year
2005
Weight
12 KB
Volume
36
Category
Article
ISSN
0931-7597

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Stereoselective synthesis of cyclic ethe
โœ Jong-Gab Jun ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 286 KB

## Abstract Bicyclic ketals in the 6,8โ€dioxabicyclo[3.2.1]octane system readily reacted with triethylsilaneโ€boron triโ€fluoride etherate at room temperature to give only the __cis__โ€tetrahydropyranol derivatives __via__ C~5~โ€O~6~ bond cleavage. __Threeโ€__ and __erythro__โ€alcohols were prepared selec