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Stereoselective Synthesis of the C(1)—C(9) Synthon (III) of Constanolactones by Biomimetic Cyclization of Homoallylic Epoxide (II).

✍ Scribed by M. A. Lapitskaya; K. K. Pivnitsky


Publisher
John Wiley and Sons
Year
2004
Weight
85 KB
Volume
35
Category
Article
ISSN
0931-7597

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✍ Alain De Mesmaeker; Pascale Hoffmann; Beat Ernst; Paul Hug; Tammo Winkler 📂 Article 📅 1989 🏛 Elsevier Science 🌐 French ⚖ 207 KB

A new strategy for the stereoselective synthesis of cz-and 13-C(1)-glycosides based on an intramolecular radical cyclization reaction is described. Intramolecular hydrogen atom transfer was observed depending on the concentration of the reagents, the conformation and the substitution of the cyclized