Stereoselective synthesis of the C-linked analogue of β-d-galactopyranosyl-l-serine

✍ Scribed by Alessandro Dondoni; Alberto Marra; Alessandro Massi

• Book ID: 104209136
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 330 KB
• Volume: 54
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(98)83019-6

✦ Synopsis

A/tstraet:. l~e coupling of the D-serinal derivative 7 with the l~.~Al~ynmosyimethylene phosph(nne generated from the phosphouium salt 6 and reduction of the resulting aHume led to the C.glycosylated amino alcohol 9 that in tmn was oxidized to Ihe title mdno acid in 44% overall yield.