A facile synthesis of the 20-hydroxyecdy
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Udo Hedtmann; Peter Welzel
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Article
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1985
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Elsevier Science
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French
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Key steps of a new synthesis of the ZO-hydroxyecdysone side chain are (i) addition of 2 to ZO-ketopregnanes and (ii) the stereoselective reduction of the 22-keto group after OH group protection. PO-Hydroxyecdysone (IZb) plays a major regulatory role during the postembryonic development of insects an