A New Stereoselective Synthesis of Grand
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Langer, Klaus ;Mattay, Jochen ;Heidbreder, Andreas ;MΓΆller, Manfred
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Article
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1992
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John Wiley and Sons
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English
β 370 KB
## Abstract Grandisol (10) is stereoselectively synthesized in 9 steps, starting from commercially available 3βmethylβ3βbutenβ1βol (1). The key step of the synthesis is the Cu(I)βcatalyzed [2 + 2]βphotocycloaddition of 3 to 4a or 4b. Moreover, solvent effects on the __endo/exo__ product ratio of th