Stereoselective synthesis of plant growth-promoting steroids, dolicholide and 28-norbrassinolide

✍ Scribed by Suguru Takatsuto; Nobuo Ikekawa

• Book ID: 104217007
• Publisher: Elsevier Science
• Year: 1983
• Tongue: French
• Weight: 223 KB
• Volume: 24
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)81524-5

✦ Synopsis

Stereoselective introduction of (22R,23R)-vicinal diol function at C-22, C-23 position of the steroidal side chain was achieved using the me,t.hod of chelation control, leading to the stereoselective synthesis of dolicholide(4) and 28-norbrassinolide(2). Stereoselective introduction of (22R,23R)-vicinal diol function at C-22, C-23 position of the steroidal side chain is a crucial step to synthesize natural plant growth hormone, brassinolide(l)' and its related compounds, since direct