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Stereoselective synthesis of novel glyco-pyrano pyrrolidines/pyrrolizidines/indolizidines through intramolecular [3+2] cycloaddition approach

โœ Scribed by N. Sirisha; R. Raghunathan


Book ID
104097592
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
379 KB
Volume
51
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


An efficient and stereoselective synthesis of novel furo-pyrano pyrrolidine/pyrrolizidine/indolizidine derivatives has been achieved by intramolecular [3+2] cycloaddition reaction of azomethine ylide generated in situ from O-allyl sugar-derived aldehyde and different secondary amino acids.


๐Ÿ“œ SIMILAR VOLUMES


Novel synthesis of naphtho[2,1-b]pyrano
โœ Subban Kathiravan; Devannah Vijayarajan; Raghavachary Raghunathan ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 888 KB

A facile synthesis of a series of naphtho[2,1-b]pyrano pyrrolizidines and indolizidines was accomplished in good yields in a one-pot reaction through intramolecular 1,3-dipolar cycloaddition of azomethine ylides with Baylis-Hillman adducts as dipolarophiles. The protocol is applicable to a wide vari