𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereoselective Synthesis of New Conformationally Restricted Analogues of a Potent CGRP Receptor Antagonist

✍ Scribed by Zuev, Dmitry; Michne, Jodi A.; Huang, Hong; Beno, Brett R.; Wu, Dedong; Gao, Qi; Torrente, John R.; Xu, Cen; Conway, Charles M.; Macor, John E.; Dubowchik, Gene M.


Book ID
127387846
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
132 KB
Volume
7
Category
Article
ISSN
1523-7060

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Synthesis of a conformationally restrict
✍ Luciano Barboni; Catia Lambertucci; Roberto Ballini; Giovanni Appendino; Ezio Bo πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 280 KB

A conformationally constrained analogue of the paclitaxel side-chain was synthesised in an enantioselective way from ethyl IH-indene-2-carboxylate. Coupling with 7-triethylsilylbaccatin III and deprotection afforded 2',2"-methylenepaclitaxel, a novel analogue of the natural product retaining antican