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Stereoselective synthesis of L-733,060

✍ Scribed by G Bhaskar; B Venkateswara Rao

Publisher: Elsevier Science
Year: 2003
Tongue: French
Weight: 117 KB
Volume: 44
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(02)02772-7

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✦ Synopsis

Enantioselective synthesis of non-peptidic neurokinin NK1 receptor antagonist L-733,060 is described using ring-closing metathesis as a key step, starting from L-phenylglycine.

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