𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Stereoselective synthesis of erythro α-amino epoxides

✍ Scribed by David P. Rotella


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
204 KB
Volume
36
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stereoselective synthesis of an erythro
✍ Masaaki Kurihara; Kei Ishii; Yoko Kasahara; Naoki Miyata 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 123 KB

Erythro a-amino epoxide, an important intermediate for synthesis of protease inhihitors, was synthesized from propargylic alcohol in a highly enantio-and diastereoselective manner.

Functionalized erythro N-protected α-ami
✍ Amnon Albeck; Gary I. Estreicher 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 753 KB

Erythro N-protected a-amino epoxides, derived from s-amino acids bearing functionalized side chains, were synthesized. The key synthetic step is a stereoselective reduction of the corresponding haloketone either to the halohydrin or directly to the epoxide. The side chains include ester, ether and a