Stereoselective Synthesis of Dipeptide β-Turn Mimetics: 7-Benzyl and 8-Phenyl Substituted Azabicyclo[4.3.0]nonane Amino Acid Esters†
✍ Scribed by Wang, Wei; Yang, Jianqing; Ying, Jinfa; Xiong, Chiyi; Zhang, Junyi; Cai, Chaozhong; Hruby, Victor J.
- Book ID
- 111672458
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 150 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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2S,3S)-and (2R,3R)-2-amino-3-phenyl-5-hexenoic acids have been synthesized in large scale by using Ni(II)-complexes as a template. The amino acids were used in the synthesis of [4,3,0]-bicyclic b-turn mimetics by a convergent methodology. The unique advantage of this strategy is the convenience of i
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