The Michael addition of lithium or magnesium organocuprates and sodium dimethyl malonate to 2-alkylated 3,4-didehydropymglutamates 7, prepared from the corresponding 4-substituted sulfoxides pyroglutamates or from benzophenone imine of glycine ethyl ester or nittile, takes place in a stereoselective
Stereoselective synthesis of 3-alkylated glutamic acids: application to the synthesis of secokainic acid
β Scribed by Jako, Isabelle; Uiber, Pierre; Mann, Andre; Wermuth, Camille Georges; Boulanger, Thierry; Norberg, Bernadette; Evrard, Guy; Durant, Francois
- Book ID
- 126075691
- Publisher
- American Chemical Society
- Year
- 1991
- Tongue
- English
- Weight
- 685 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0022-3263
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