Stereoselective synthesis of (2S,3S,4R,5S)-3,4-dihydroxy-2,5-dihydroxymethyl pyrrolidine from l-sorbose
✍ Scribed by Balieu, Sébastien; Guilleret, Arnaud; Reynaud, Romain; Martinez, Agathe; Haudrechy, Arnaud
- Book ID
- 120269359
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 686 KB
- Volume
- 374
- Category
- Article
- ISSN
- 0008-6215
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A catalytic deuteration of protected 3,4-dehydro-L-proline using RuCI2(PPh3) 3 followed by RuO~-oxidation gave a 3,4-dideuterated L-pyroglutamic acid derivative which is considered to be a promising precursor for various deuterated amino acids. The present study demonstrates a stereoselective reduct
A facile approach to the versatile chiral building block 2 was developed based on glutamic acid, whereby a new method for asymmetric synthesis of sex pheromone 1 was explored from cheap glutamic acid.
The first total synthesis of (3S,4R)-dihydroxy-(6S)-undecyl-a-pyranone 1 and total synthesis of (2S,3R,5S)-(À)-2,3-dihydroxytetradecan-5-olide 2 have been achieved in five steps in a highly stereoselective manner using Maruoka allylation, olefin cross-metathesis, and Sharpless asymmetric dihydroxyla