Stereoselective synthesis of 2,3,7-trime
β
Junpei Naito; Shunsuke Kuwahara; Masataka Watanabe; John Decatur; Pieter H. Bos;
π
Article
π
2008
π
John Wiley and Sons
π
English
β 303 KB
## Abstract The copper/chiral phosphoramidite (**L~1~**)βcatalyzed conjugate addition of dimethylzinc to cyclooctaβ2,7βdienone **4**, followed by the methylation of the intermediate enolate, yielded a single isomer of 7,8βdimethylcyclooctβ2βenone (+)β**5**. Compound (+)β**5** was subjected to the s