Stereoselective Synthesis of 2-(2-Hydroxyalkyl)piperidine Alkaloids Through Prins–Ritter Reaction
✍ Scribed by Subba Reddy, B. V.; Ghanty, Supriya; Reddy, N. Siva Senkar; Reddy, Y. Jayasudhan; Yadav, J. S.
- Book ID
- 123619461
- Publisher
- Taylor and Francis Group
- Year
- 2014
- Tongue
- English
- Weight
- 327 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0039-7911
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AbstractÐThis paper describes a new general approach towards functionalized piperidine alkaloids, based on the stereo-and regioselective palladium(0)-catalyzed nucleophilic ring-opening of vinyl epoxides by nitrogen nucleophiles. The latter reaction provides access to stereo-de®ned anti and syn amin