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Stereoselective synthesis of 1,3-syn-3,5-anti-triols using a syn-1,3-asymmetric reduction: A novel route to anti-1,3-polyols

โœ Scribed by Yuji Mori; Makoto Suzuki


Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
244 KB
Volume
30
Category
Article
ISSN
0040-4039

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Stereoselective reduction of ฮฒ-alkoxy ke
โœ Yuji Mori; Miki Kuhara; Akio Takeuchi; Makoto Suzuki ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 238 KB

The diastereoselective reduction of acyclic B-alkoxy ketones with lithium aluminum hydride in the presence of lithium iodide has been studied and found to provide syn-1,3-diol derivatives with high diastereoselection. -The stereocontrolled formation of 1,3-diols is of great interest to synthetic che