Stereoselective synthesis of l-vancosami
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Ralph Greven; Peter Jütten; Hans-Dieter Scharf
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Article
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1995
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Elsevier Science
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English
⚖ 656 KB
The methyl fl-glycopyranoside of L-vancosamine (1, 3-amino-2,3,6-trideoxy-3-C-methyl-Llyxo-hexose), a constituent of vancomycin and related glycopeptide antibiotics, was synthesized stereoselectively from methyl 2,6-dideoxy-fl-L-lyxo-hexopyranoside (2) in eight steps. Compound 2 was subjected in seq