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Stereoselective sulfoxide directed reduction of 1,2-diketo-derivatives to enantiomerically pure syn and anti 1,2-diols. Correction of the relative configuration by X-ray and chemical correlation to goniobutenolides A and B

✍ Scribed by Guy Solladié; Gilles Hanquet; Catherine Rolland


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
191 KB
Volume
40
Category
Article
ISSN
0040-4039

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Stereoselective sulfoxide directed reduc
✍ Guy Solladié; Gilles Hanquet; Catherine Rolland 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 196 KB

A new route to enantiopure syn and anti 1,2-diols is described from oxalyl-di-(Nmethyl-N-methoxyamide) via the corresponding ~-ketosulfoxide. This is the first report of the stereoselective reduction ofaT--keto-~-hydroxysulfoxide.