Stereoselective sonochemical reductive silylation of geminal dibromocyclopropanes by bulk magnesium

✍ Scribed by Jonathan Touster; Albert J. Fry

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 207 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)01453-6

✦ Synopsis

Ultrasonic irradiation of a THF solution containing both trimethysilyl chloride and a bicyclic 1,l-dibromocyclopropane in the presence of bulk magnesium affords 1-trimethylsilyl-l-bromocyclopropanes in 72-93% yield. The sonochemical reactions proceed stereoselectively to afford as the major product the product in which the trimethylsilyl group is cis to the hydrogen atoms at the ring juncture.