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Stereoselective SN2 Reactions of the (R)-Pantolactone Ester of Racemic .alpha.-Halo Carboxylic Acids with Aryl Oxides. A Synthesis of (S)-2-Aryloxy and (S)-2-Hydroxy Acids

โœ Scribed by Koh, Kevin; Durst, Tony


Book ID
121220719
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
496 KB
Volume
59
Category
Article
ISSN
0022-3263

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Introduction. ~ Stereoselective C-C bond forming reactions catalyzed by chiral transition-metal complexes are a topic of fundamental importance [l]. In 1986, Hayashi and Zto reported an elegant asymmetric synthesis of dihydrooxazoles by an efficient gold(1)-catalyzed coupling of aldehydes with 2-iso