✦ LIBER ✦
Stereoselective semi-hydrogenation and deuteration of a diacetylenic precursor of leukotriene B4 methyl ester
✍ Scribed by Renée Pontikis; Yves Le Merrer; Jean-Claude Depezay; Yves Pétillot; Bernard Rousseau; Jean Pierre Beaucourt
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- French
- Weight
- 275 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
[6,7,14,15‐^2^H~4~)‐Leukotriene B~4~ methyl ester was prepared by reduction with deuterium gas of a suitable precursor (deuterium incorporation ≥ 90%). Several catalytic semi‐hydrogenations were effected in order to determine the best conditions for the labeling step.