Stereoselective protein binding of verapamil enantiomers
โ Scribed by Annette S. Gross; Barbara Heuer; Michel Eichelbaum
- Book ID
- 115780340
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 552 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0006-2952
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Stereoselective differences in pharmacokinetics between clausenamide (CLA) enantiomers have been found after intravenous and oral administration of each enantiomer to rats. The differences could be associated with protein binding of CLA enantiomers. By equilibrium dialysis methods, the binding of CL