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Stereoselective pharmacological effects and benzodiazepine receptor affinity of the enantiomers of Gö 4962

✍ Scribed by Bartoszyk, G. D.; Dooley, D. J.; Barth, H.; Hartenstein, J.; Satzinger, G.

Book ID
127315040
Publisher
Pharmaceutical Press
Year
1987
Tongue
English
Weight
167 KB
Volume
39
Category
Article
ISSN
2042-7158

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We report the preparative separation of rac-zopiclone using malic acid as the resolving agent. Furthermore, two different methods for the analytical determination of zopiclone enantiomers by HPLC on chiral stationary phases are described. The benzodiazepine receptor binding of the isolated enantiome