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Stereoselective one-pot synthesis of highly differently substituted thiochromans

✍ Scribed by Andrea Seifert; Rainer Mahrwald


Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
194 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


A highly stereoselective one-pot procedure to anti-configured thiochromans is described. This reaction functions at room temperature in the presence of catalytic amounts of trifluoroacetic acid. The transformation gives a selective but optional access to highly substituted thiochromans, which have been not attainable until now.


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