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Stereoselective ionic hydrogenation of Vinca alkaloids and vinorelbine in superacids: an access to 4′R-reduced analogs

✍ Scribed by Cécile Lafitte; Marie-Paule Jouannetaud; Jean-Claude Jacquesy; Jacques Fahy; Alain Duflos


Book ID
104260120
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
140 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis


Stereoselective ionic hydrogenation of vinblastine, anhydrovinblastine and vinorelbine in HF/SbF~ by methylcyclopentane yields the corresponding 4'R reduced analogs. Deuterium labelling