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Stereoselective hydrofluorination of ynamides: a straightforward synthesis of novel α-fluoroenamides

✍ Scribed by Compain, Guillaume; Jouvin, Kevin; Martin-Mingot, Agnès; Evano, Gwilherm; Marrot, Jérome; Thibaudeau, Sébastien


Book ID
125848570
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
719 KB
Volume
48
Category
Article
ISSN
1359-7345

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✍ Patricia Castejón; Albert Moyano; Miquel A. Pericàs; Antoni Riera 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 795 KB

A novel strategy for the synthesis of isostatine derivatives has been developed. Contrary to previous approaches to isostatine, a non-proteinogenic amino acid that is an essential component of the didemnins, the present synthesis does not require the intermediacy of the expensive amino acid D-do-iso